RNA interference approaches for plant disease control

Biotechnology and Plant Disease Control-Role of RNA Interference

Development of crop varieties which are resistant against many economically important diseases is a major challenge for plant biotechnologists worldwide. Although much progress in this area has been achieved through classical genetic approaches, this goal can be achieved in a more selective and robust manner with the success of genetic engineering techniques. In this regard, RNA interference (R...

Plant RNA interference in vitro.

RNA Interference for Mosquito and Mosquito-Borne Disease Control

RNA interference (RNAi) is a powerful tool to silence endogenous mosquito and mosquito-borne pathogen genes in vivo. As the number of studies utilizing RNAi in basic research grows, so too does the arsenal of physiological targets that can be developed into products that interrupt mosquito life cycles and behaviors and, thereby, relieve the burden of mosquitoes on human health and well-being. A...

RNA Interference in Insect Vectors for Plant Viruses

Insects and other arthropods are the most important vectors of plant pathogens. The majority of plant pathogens are disseminated by arthropod vectors such as aphids, beetles, leafhoppers, planthoppers, thrips and whiteflies. Transmission of plant pathogens and the challenges in managing insect vectors due to insecticide resistance are factors that contribute to major food losses in agriculture....

RNA interference and human disease.

The completion of the human genome project has left researchers searching for an efficient method to study gene function in mammalian cells. RNA interference (RNAi) is an evolutionarily conserved post-transcriptional gene silencing (PTGS) mechanism mediated by double-stranded RNA (dsRNA). The dsRNA is processed into small duplex RNA molecules of approximately 21-22 nucleotides (nts) termed smal...